DESCRIPTION
Pragmatic trials are intended to help typical clinicians and typical patients make difficult decisions in typical clinical care settings by maximizing the chance that the trial results will apply to patients that are usually seen in practice (external validity). – Sox 2016
LEARNING OBJECTIVES
- Describe the evolution of the efficacy trial to the pragmatic.
- Use systematic approaches to design and evaluate pragmatic trials.
- Describe practical approaches and resources to ensure administrative, clinical and patient preferences in design.
PRESENTER(S)
Megan Branda, MS, has planned and managed clinical trials for over 15 years. She has been a member of three national cancer cooperative groups by planning and analyzing phase I - III randomized clinical trials. She supports the research endeavors of the Mayo Clinic's KER Unit by collaborating on the design and analysis of practice based interventions as well as pragmatic clinical trials. She is the associate editors fro Trials Journal as well as the instructor of a graduate course on clinical trials design at the University of Colorado.